| 2021-08-07 17:00:547. 8. 2021 | SK SIKO Čimelice  | 1 - 2 |  FK Protivín “A” | Report |
| 2021-08-14 15:00:4314. 8. 2021 | FK Protivín “A” | 1 - 4 |  Č. Krumlov | Report |
| 2021-08-22 17:00:2522. 8. 2021 | SK Jankov  | 2 - 0 | FK Protivín “A” | Report |
| 2021-08-28 15:00:2228. 8. 2021 | FK Protivín “A” | 2 - 2 |  FK Olešník | Report |
| 2021-09-04 15:00:564. 9. 2021 | FK Protivín “A” | 0 - 0 |  TJ Dražice | Report |
| 2021-09-12 17:00:1012. 9. 2021 | FC ZVVZ Milevsko  | 2 - 0 | FK Protivín “A” | Report |
| 2021-09-18 10:15:1718. 9. 2021 | FK Protivín “A” | 1 - 3 |  TJ Osek | Report |
| 2021-09-25 16:30:4725. 9. 2021 | SK Rudolfov  | 1 - 2 | FK Protivín “A” | Report |
| 2021-09-28 15:00:2928. 9. 2021 | FK Protivín “A” | 1 - 0 |  FK Junior Strakonice | Report |
| 2021-10-02 15:00:002. 10. 2021 | FK Protivín “A” | 0 - 1 |  FK Jiskra Třeboň | Report |
| 2021-10-09 15:30:299. 10. 2021 | FK Olympie Týn nad Vltavou  | 3 - 1 | FK Protivín “A” | Report |
| 2021-10-16 15:00:1916. 10. 2021 | FK Protivín “A” | 7 - 1 |  Sokol Sezimovo Ústí | Report |
| 2021-10-23 10:15:4323. 10. 2021 | FC MAS Táborsko B  | 6 - 3 | FK Protivín “A” | Report |
| 2021-10-30 14:00:3330. 10. 2021 | FK Protivín “A” | 1 - 1 |  FK Tatran Prachatice | Report |
| 2021-11-06 14:00:046. 11. 2021 | TJ Blatná  | 2 - 4 | FK Protivín “A” | Report |
| 2022-03-13 15:00:4713. 3. 2022 | FK Junior Strakonice | 2 - 1 | FK Protivín “A” | Report |
| 2022-03-19 15:00:5219. 3. 2022 | FK Protivín “A” | 6 - 0 | SK SIKO Čimelice | Report |
| 2022-03-26 15:00:3526. 3. 2022 | Č. Krumlov | 2 - 0 | FK Protivín “A” | Report |
| 2022-04-09 16:30:489. 4. 2022 | FK Olešník | 4 - 1 | FK Protivín “A” | Report |
| 2022-04-13 17:00:0113. 4. 2022 | FK Protivín “A” | 1 - 2 | SK Jankov | Report |
| 2022-04-16 17:00:4016. 4. 2022 | TJ Dražice | 3 - 4 | FK Protivín “A” | Report |
| 2022-04-23 15:00:5723. 4. 2022 | FK Protivín “A” | 1 - 3 | FC ZVVZ Milevsko | Report |
| 2022-04-30 17:00:1830. 4. 2022 | TJ Osek | 2 - 1 | FK Protivín “A” | Report |
| 2022-05-07 15:00:577. 5. 2022 | FK Protivín “A” | 5 - 1 | SK Rudolfov | Report |
| 2022-05-15 10:30:2215. 5. 2022 | FK Jiskra Třeboň | 2 - 0 | FK Protivín “A” | Report |
| 2022-05-22 15:00:4622. 5. 2022 | FK Protivín “A” | 15:00:4615:00 | FK Olympie Týn nad Vltavou | Náhled |
